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Erwin E Sterchi Selected Research

astacin

10/2012MeprinĪ± transactivates the epidermal growth factor receptor (EGFR) via ligand shedding, thereby enhancing colorectal cancer cell proliferation and migration.
5/2008The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion.
5/2007Two alpha subunits and one beta subunit of meprin zinc-endopeptidases are differentially expressed in the zebrafish Danio rerio.
3/2004Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors.
10/2003Phorbol 12-myristate 13-acetate-induced ectodomain shedding and phosphorylation of the human meprinbeta metalloprotease.

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Erwin E Sterchi Research Topics

Disease

9Neoplasms (Cancer)
10/2012 - 10/2002
4Colorectal Neoplasms (Colorectal Cancer)
10/2012 - 10/2002
2Alzheimer Disease (Alzheimer's Disease)
05/2016 - 01/2016
1Adenocarcinoma
10/2012
1Adenoma (Adenomas)
01/2011
1Neoplasm Metastasis (Metastasis)
01/2011
1Keloid
12/2010
1Crohn Disease (Crohn's Disease)
01/2010
1Cystic Fibrosis (Mucoviscidosis)
11/2008
1Membranous Glomerulonephritis (Membranous Nephropathy)
05/2008
1Glomerulonephritis
05/2008
1Confusion (Bewilderment)
07/2007
1Psoriasis (Pustulosis Palmaris et Plantaris)
05/2007
1Inflammation (Inflammations)
03/2007
1Necrosis
03/2004
1Congenital Lactase Deficiency
10/2002
1Weight Gain
10/2002

Drug/Important Bio-Agent (IBA)

12Tiopronin (Thiola)FDA Link
05/2016 - 10/2002
7Metalloproteases (Metalloproteinases)IBA
10/2012 - 03/2004
5Proteins (Proteins, Gene)FDA Link
05/2016 - 10/2003
5astacinIBA
10/2012 - 10/2003
3Peptides (Polypeptides)IBA
05/2016 - 03/2007
3ZincIBA
05/2007 - 10/2003
2Amyloid (Amyloid Fibrils)IBA
05/2016 - 01/2016
2Peptide Hydrolases (Proteases)FDA Link
01/2011 - 10/2002
2EnzymesIBA
07/2007 - 03/2004
2EndopeptidasesIBA
05/2007 - 03/2004
1Epidermal Growth Factor (EGF)IBA
10/2012
1LigandsIBA
10/2012
1ErbB Receptors (EGF Receptor)IBA
10/2012
1CytokinesIBA
10/2012
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2012
1DisulfidesIBA
10/2012
1Enzyme Precursors (Zymogens)IBA
01/2011
1Messenger RNA (mRNA)IBA
01/2011
1TenascinIBA
01/2010
1Cadherins (E-Cadherin)IBA
05/2008
1alpha-Glucosidases (Acid Maltase)IBA
07/2007
1prolyl-leucyl-glycine hydroxamateIBA
03/2004
1batimastat (BB 94)IBA
03/2004
1N- (2(R)- 2- (hydroxamidocarbonylmethyl)- 4- methylpentanoyl)- L- tryptophan methylamideIBA
03/2004
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2004
1Captopril (Capoten)FDA LinkGeneric
03/2004
1Protease Inhibitors (Protease Inhibitor)IBA
03/2004
1TAPI-2IBA
03/2004
1Hydroxamic Acids (Hydroxamic Acid)IBA
03/2004
1Sulfhydryl Compounds (Thiols)IBA
03/2004
1Matrix Metalloproteinases (MMPs)IBA
03/2004
1Metalloendopeptidases (Metalloendopeptidase)IBA
10/2003
1FibrinolysinFDA Link
05/2003
1PlasminogenIBA
10/2002
1Glucose (Dextrose)FDA LinkGeneric
10/2002